10x Science

Founded by David S. Roberts in 2024

Characterize proteins and analyze complex peptide mapping data in real time

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You can use 10x Science to analyze complex protein therapeutics data and accelerate molecular characterization. The system performs automated peptide mapping and de novo sequencing without requiring manual file conversions across different mass spectrometry instruments. It identifies post-translational modifications such as glycosylation, detects unexpected sequence variants, and resolves distinct proteoforms to evaluate drug quality. With local asynchronous processing alongside cloud streaming, research teams inspect targeted, middle-down, and top-down fragmentation spectra directly in their browser to confirm protein target identities and speed therapeutic development.

What 10x Science does

Inspect mass spectrometry fragmentation spectra with interactive zoomCalculate sequence coverage and average mass error in parts per millionBuild custom modification profiles for target amino acid sequencesSearch proteoform families against UniProt reference databasesResolve combinatorial post-translational modifications across protein chainsProcess raw omics instrument files asynchronously without file format conversionsHigh-speed peptide mapping for protein therapeuticsDe novo top-down and middle-down sequencing analysisAutomated identification and quantification of complex combinatorial PTMsInteractive spectrum viewer for high-density peak datasetsVendor-neutral mass spectrometry file ingestion without conversionsDirect integration with UniProt and support for custom proteoform librariesLocal asynchronous data processing with cloud database streaming

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